Formation of Magnetic Structures for Trapping of Breast Cancer Cell

Alaa Alasadi; Ali Ghanim Gatea Al Rubaye

doi:10.3740/MRSK.2024.34.3.144

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2024 Vol.34, Issue 3 Preview Page Next Page

Research Paper

Formation of Magnetic Structures for Trapping of Breast Cancer Cell

27 March 2024. pp. 144-151

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Abstract

This work focuses on the fabrication of excellent magnetic structures for trapping breast cancer cells. Micro-magnetic structures were patterned for trapping cancer cells by depositing 30 nm of permalloy on a silicon substrate. These structures were designed and fabricated using two fabrication techniques: electron beam lithography and laser direct writing. Two types of magnetic structures, rectangular wire and zig-zagged wire, were created on a silicon substrate. The length of each rectangular wire and each straight line of zig-zagged wire was 150 µm with a range of widths from 1 to 15 µm for rectangular and 1, 5, 10 and 15 µm for zigzag, respectively. The magnetic structures showed good responses to the applied magnetic field despite adding layers of silicon nitride and polyethylene glycol. The results showed that Si + Si₃N₄ + PEG exhibited the best adhesion of cells to the surface, followed by Si + Py + Si₃N₄ + PEG. concentration of 5-6 with permalloy indicates that this layer affected silicon nitride in the presence of Polyethylene glycolPEG.

Keywords

electron beam lithography

cell trapping

magnetic structures

culture media

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Information

Publisher :Materials Research Society of Korea
Publisher(Ko) :한국재료학회
Journal Title :Korean Journal of Materials Research
Journal Title(Ko) :한국재료학회지
Volume : 34
No :3
Pages :144-151
Received Date : 2023-09-27
Revised Date : 2024-03-10
Accepted Date : 2024-03-12
DOI :https://doi.org/10.3740/MRSK.2024.34.3.144

Korean Journal of Materials Research ISSN:1225-0562(Print) 2287-7258(Online) 한국재료학회지

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