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2023 Vol.33, Issue 2 Preview Page

Research Paper

Physical Properties, Antimicrobial Efficacy, and Biocompatibility of Denture Base Resins Coated with Natural Peony Extract
Myung-Jin Lee1*
,
Yu-Ri Choi2*
,
Min-Kyung Kang3†
1Department of Dental Hygiene, Division of Health Science, Baekseok University, Cheonan 31065, Republic of Korea
2Department of Dental Hygiene, Hallym Polytechnic University, Chuncheon 24210, Republic of Korea
3Department of Dental Hygiene, Hanseo University, Seosan 31963, Republic of Korea
†Corresponding author E-Mail : kmk0709@hanseo.ac.kr (M.-K. Kang, Hanseo Univ.)

*These two authors are equally contributed as first authors.

27 February 2023. pp. 47-53
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Abstract

When exposed to different types of bacteria in the oral cavity, denture based resins are prone to bacteria attachment. The purpose of this study was to investigate the physical, biological, and antimicrobial properties of denture base resins coated with Peony extract (200, 400, and 600 µg/mL). Specifically, the surface properties (microhardness, contact angle, and color change of the coated specimens), cell cytotoxicity (measured using MTT assay), and antimicrobial activity (against S. mutans (Streptococcus mutans) and C. albicans (Candida albicans) using a growth inhibition assay) were evaluated. The polyphenol content was measured using ultraviolet-visible (UV-vis) spectrometry. The experimental groups (specimens coated with Peony extract) and a control group (specimens coated without Peony extract) were statistically compared using a one-way analysis of variance and Tukey’s post-hoc tests. No statistically significant differences in surface properties or cell cytotoxicity were observed, which demonstrated their biocompatibility. Conversely, a statistically significant difference in antimicrobial activity was observed between the experimental and control groups after 48 h. This confirms the antimicrobial activity of the denture base resin coated with Peony extract and demonstrates that it is a promising dental material for preventing stomatitis.

Keywords
antimicrobial properties
biocompatibility
denture base resin
surface characterization
peony extract
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Information
  • Publisher :Materials Research Society of Korea
  • Publisher(Ko) :한국재료학회
  • Journal Title :Korean Journal of Materials Research
  • Journal Title(Ko) :한국재료학회지
  • Volume : 33
  • No :2
  • Pages :47-53
  • Received Date : 2023-01-25
  • Revised Date : 2023-01-30
  • Accepted Date : 2023-01-31
  • DOI :https://doi.org/10.3740/MRSK.2023.33.2.47
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